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Mast cell tolerance in the skin microenvironment to commensal bacteria is controlled by fibroblasts

Activation and degranulation of mast cells (MCs) is an essential aspect of innate and adaptive immunity. Skin MCs, the most exposed to the external environment, are at risk of quickly degranulating with potentially severe consequences. Here, we define how MCs assume a tolerant phenotype via crosstal...

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Detalles Bibliográficos
Autores principales: Nardo, Anna Di, Chang, Yu-Ling, Alimohammadi, Shahrzad, Masuda-Kuroki, Kana, Wang, Zhenping, Sriram, Krishna, Insel, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290424/
https://www.ncbi.nlm.nih.gov/pubmed/37120813
http://dx.doi.org/10.1016/j.celrep.2023.112453