Deep proteome investigation of high-grade gliomas reveals heterogeneity driving differential metabolism of 5-aminolevulinic acid

BACKGROUND: Fluorescence-guided surgery (FGS) using 5-aminolevulinic acid (5-ALA) as adjunct for high-grade gliomas (HGGs) has been on the rise in recent years. Despite being largely effective, we observed multiple histologically similar sub-regions of the same tumor from a few individuals with vary...

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Detalles Bibliográficos
Autores principales: Ghantasala, Saicharan, Bhat, Amruth, Agarwal, Unnati, Biswas, Deeptarup, Bhattarai, Prawesh, Epari, Sridhar, Moiyadi, Aliasgar, Srivastava, Sanjeeva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290514/
https://www.ncbi.nlm.nih.gov/pubmed/37358939
http://dx.doi.org/10.1093/noajnl/vdad065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290514/
https://www.ncbi.nlm.nih.gov/pubmed/37358939
http://dx.doi.org/10.1093/noajnl/vdad065

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