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The sequence of the repetitive motif influences the frequency of multistep mutations in Short Tandem Repeats

Microsatellites, or Short Tandem Repeats (STRs), are subject to frequent length mutations that involve the loss or gain of an integer number of repeats. This work aimed to investigate the correlation between STRs’ specific repetitive motif composition and mutational dynamics, specifically the occurr...

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Detalles Bibliográficos
Autores principales: Antão-Sousa, Sofia, Pinto, Nádia, Rende, Pablo, Amorim, António, Gusmão, Leonor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290632/
https://www.ncbi.nlm.nih.gov/pubmed/37355683
http://dx.doi.org/10.1038/s41598-023-32137-y