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PDE4DIP contributes to colorectal cancer growth and chemoresistance through modulation of the NF1/RAS signaling axis

Phosphodiesterase 4D interacting protein (PDE4DIP) is a centrosome/Golgi protein associated with cyclic nucleotide phosphodiesterases. PDE4DIP is commonly mutated in human cancers, and its alteration in mice leads to a predisposition to intestinal cancer. However, the biological function of PDE4DIP...

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Detalles Bibliográficos
Autores principales: Pan, Rulu, Dai, Juji, Liang, Weicheng, Wang, Hongxiao, Ye, Lin, Ye, Siqi, Lin, Ziqi, Huang, Shishun, Xiong, Yan, Zhang, Li, Lu, Liting, Wang, Ouchen, Shen, Xian, Liao, Wanqin, Lu, Xincheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290635/
https://www.ncbi.nlm.nih.gov/pubmed/37355626
http://dx.doi.org/10.1038/s41419-023-05885-y