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Acute muscle mass loss was alleviated with HMGB1 neutralizing antibody treatment in severe burned rats
Burn injury is associated with muscle wasting, though the involved signaling mechanisms are not well understood. In this study, we aimed to examine the role of high mobility group box 1 (HMGB1) in signaling hyper-inflammation and consequent skeletal muscle impairment after burn. Sprague Dawley rats...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290662/ https://www.ncbi.nlm.nih.gov/pubmed/37355693 http://dx.doi.org/10.1038/s41598-023-37476-4 |