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Acute muscle mass loss was alleviated with HMGB1 neutralizing antibody treatment in severe burned rats

Burn injury is associated with muscle wasting, though the involved signaling mechanisms are not well understood. In this study, we aimed to examine the role of high mobility group box 1 (HMGB1) in signaling hyper-inflammation and consequent skeletal muscle impairment after burn. Sprague Dawley rats...

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Detalles Bibliográficos
Autores principales: Song, Juquan, Chowdhury, Imran H., Choudhuri, Subhadip, Ayadi, Amina E. I., Rios, Lizette E., Wolf, Steven E., Wenke, Joseph C., Garg, Nisha J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290662/
https://www.ncbi.nlm.nih.gov/pubmed/37355693
http://dx.doi.org/10.1038/s41598-023-37476-4