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Hyperphagia of female UCP1-deficient mice blunts anti-obesity effects of FGF21

Increasing energy expenditure through uncoupling protein 1 (UCP1) activity in thermogenic adipose tissue is widely investigated to correct diet-induced obesity (DIO). Paradoxically, UCP1-deficient male mice are resistant to DIO at room temperature. Recently, we uncovered a key role for fibroblast gr...

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Detalles Bibliográficos
Autores principales: Klein Hazebroek, Marlou, Laterveer, Rutger, Kutschke, Maria, Ramšak Marčeta, Vida, Barthem, Clarissa S., Keipert, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290677/
https://www.ncbi.nlm.nih.gov/pubmed/37355753
http://dx.doi.org/10.1038/s41598-023-37264-0