An unnatural enzyme with endonuclease activity towards small non-coding RNAs

Endonucleases are enzymes that cleave internal phosphodiester bonds within double-stranded DNA or RNA and are essential for biological functions. Herein, we use genetic code expansion to create an unnatural endonuclease that cleaves non-coding RNAs including short interfering RNA (siRNA) and microRN...

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Detalles Bibliográficos
Autores principales: Ahmed, Noreen, Ahmed, Nadine, Bilodeau, Didier A., Pezacki, John Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290691/
https://www.ncbi.nlm.nih.gov/pubmed/37355703
http://dx.doi.org/10.1038/s41467-023-39105-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290691/
https://www.ncbi.nlm.nih.gov/pubmed/37355703
http://dx.doi.org/10.1038/s41467-023-39105-0

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