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Dissecting sources of variability in patient response to targeted therapy: anti-HER2 therapies as a case study

BACKGROUND AND PURPOSE: Despite their use to treat cancers with specific genetic aberrations, targeted therapies elicit heterogeneous responses. Sources of variability are critical to targeted therapy drug development, yet there exists no method to discern their relative contribution to response het...

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Detalles Bibliográficos
Autores principales: Qi, Timothy, Cao, Yanguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290754/
https://www.ncbi.nlm.nih.gov/pubmed/37196833
http://dx.doi.org/10.1016/j.ejps.2023.106467