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Dissecting sources of variability in patient response to targeted therapy: anti-HER2 therapies as a case study
BACKGROUND AND PURPOSE: Despite their use to treat cancers with specific genetic aberrations, targeted therapies elicit heterogeneous responses. Sources of variability are critical to targeted therapy drug development, yet there exists no method to discern their relative contribution to response het...
Autores principales: | Qi, Timothy, Cao, Yanguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290754/ https://www.ncbi.nlm.nih.gov/pubmed/37196833 http://dx.doi.org/10.1016/j.ejps.2023.106467 |
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