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HMGCR gene polymorphism is associated with residual cholesterol risk in premature triple-vessel disease patients treated with moderate-intensity statins

BACKGROUND: To investigate the association of HMGCR and NPC1L1 gene polymorphisms with residual cholesterol risk (RCR) in patients with premature triple-vessel disease (PTVD). METHODS: Three SNPs within HMGCR including rs12916, rs2303151, and rs4629571, and four SNPs within NPC1L1 including rs117637...

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Detalles Bibliográficos
Autores principales: Li, Jiawen, Tang, Xiaofang, Xu, Jingjing, Liu, Ru, Jiang, Lin, Xu, Lianjun, Tian, Jian, Feng, Xinxing, Wu, Yajie, Zhang, Yin, Wang, Dong, Sun, Kai, Xu, Bo, Zhao, Wei, Hui, Rutai, Gao, Runlin, Song, Lei, Yuan, Jinqing, Zhao, Xueyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290797/
https://www.ncbi.nlm.nih.gov/pubmed/37355634
http://dx.doi.org/10.1186/s12872-023-03285-w