Itaconic acid underpins hepatocyte lipid metabolism in non-alcoholic fatty liver disease in male mice

Itaconate, the product of the decarboxylation of cis-aconitate, regulates numerous biological processes. We and others have revealed itaconate as a regulator of fatty acid β-oxidation, generation of mitochondrial reactive oxygen species and the metabolic interplay between resident macrophages and tu...

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Detalles Bibliográficos
Autores principales: Weiss, Jonathan M., Palmieri, Erika M., Gonzalez-Cotto, Marieli, Bettencourt, Ian A., Megill, Emily L., Snyder, Nathaniel W., McVicar, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290955/
https://www.ncbi.nlm.nih.gov/pubmed/37308721
http://dx.doi.org/10.1038/s42255-023-00801-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290955/
https://www.ncbi.nlm.nih.gov/pubmed/37308721
http://dx.doi.org/10.1038/s42255-023-00801-2

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