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Adipogenic and SWAT cells separate from a common progenitor in human brown and white adipose depots

Adipocyte function is a major determinant of metabolic disease, warranting investigations of regulating mechanisms. We show at single-cell resolution that progenitor cells from four human brown and white adipose depots separate into two main cell fates, an adipogenic and a structural branch, develop...

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Detalles Bibliográficos
Autores principales: Palani, Nagendra P., Horvath, Carla, Timshel, Pascal N., Folkertsma, Pytrik, Grønning, Alexander G. B., Henriksen, Tora I., Peijs, Lone, Jensen, Verena H., Sun, Wenfei, Jespersen, Naja Z., Wolfrum, Christian, Pers, Tune H., Nielsen, Søren, Scheele, Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290958/
https://www.ncbi.nlm.nih.gov/pubmed/37337126
http://dx.doi.org/10.1038/s42255-023-00820-z