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Disulfide-incorporated lipid prodrugs of cidofovir: Synthesis, antiviral activity, and release mechanism

The double-stranded DNA (dsDNA) viruses represented by adenovirus and monkeypox virus, have attracted widespread attention due to their high infectivity. In 2022, the global outbreak of mpox (or monkeypox) has led to the declaration of a Public Health Emergency of International Concern. However, to...

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Detalles Bibliográficos
Autores principales: Wang, Baogang, Cao, Binwang, Bei, Zhu-Chun, Xu, Likun, Zhang, Dongna, Zhao, Liangliang, Song, Yabin, Wang, Hongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290961/
https://www.ncbi.nlm.nih.gov/pubmed/37390509
http://dx.doi.org/10.1016/j.ejmech.2023.115601