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Longitudinal characterization of primary osteosarcoma and derived subcutaneous and orthotopic relapsed patient-derived xenograft models

Osteosarcoma is a rare bone cancer in adolescents and young adults with a dismal prognosis because of metastatic disease and chemoresistance. Despite multiple clinical trials, no improvement in outcome has occurred in decades. There is an urgent need to better understand resistant and metastatic dis...

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Detalles Bibliográficos
Autores principales: da Costa, Maria Eugenia Marques, Droit, Robin, Khneisser, Pierre, Gomez-Brouchet, Anne, Adam-de-Beaumais, Tiphaine, Nolla, Marie, Signolles, Nicolas, Torrejon, Jacob, Lombard, Bérangère, Loew, Damarys, Ayrault, Olivier, Scoazec, Jean-Yves, Geoerger, Birgit, Vassal, Gilles, Marchais, Antonin, Gaspar, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291137/
https://www.ncbi.nlm.nih.gov/pubmed/37377921
http://dx.doi.org/10.3389/fonc.2023.1166063