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Flux estimation analysis systematically characterizes the metabolic shifts of the central metabolism pathway in human cancer

INTRODUCTION: Glucose and glutamine are major carbon and energy sources that promote the rapid proliferation of cancer cells. Metabolic shifts observed on cell lines or mouse models may not reflect the general metabolic shifts in real human cancer tissue. METHOD: In this study, we conducted a comput...

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Detalles Bibliográficos
Autores principales: Yang, Grace, Huang, Shaoyang, Hu, Kevin, Lu, Alex, Yang, Jonathan, Meroueh, Noah, Dang, Pengtao, Wang, Yijie, Zhu, Haiqi, Cao, Sha, Zhang, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291142/
https://www.ncbi.nlm.nih.gov/pubmed/37377905
http://dx.doi.org/10.3389/fonc.2023.1117810