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Glycolytic enzyme HK2 promotes PD-L1 expression and breast cancer cell immune evasion

Immune therapies targeting the PD-1/PD-L1 pathway have been employed in the treatment of breast cancer, which requires aerobic glycolysis to sustain breast cancer cells growth. However, whether PD-L1 expression is regulated by glycolysis in breast cancer cells remains to be further elucidated. Here,...

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Detalles Bibliográficos
Autores principales: Lin, Jichun, Fang, Wenshuo, Xiang, Zhuo, Wang, Qingqing, Cheng, Huapeng, Chen, Shimin, Fang, Jing, Liu, Jia, Wang, Qiang, Lu, Zhimin, Ma, Leina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291184/
https://www.ncbi.nlm.nih.gov/pubmed/37377974
http://dx.doi.org/10.3389/fimmu.2023.1189953