Investigation of Methyl-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxyhydrazide Derivatives as Potential Inhibitors of COVID-19 Main Protease: DFT and Molecular Docking Study

The search for effective therapeutics to combat COVID-19 has led to the exploration of the biological activity of numerous compounds. In this study, hydrazones derived from oseltamivir intermediate, methyl 5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylate have been investigated for thei...

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Detalles Bibliográficos
Autores principales: Akinyele, Olawale Folorunso, Fakola, Emmanuel Gabriel, Adeboye, Omolara Olubunmi, Chinuomah, Sunday Chimela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291222/
https://www.ncbi.nlm.nih.gov/pubmed/37377795
http://dx.doi.org/10.1177/11779322231182050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291222/
https://www.ncbi.nlm.nih.gov/pubmed/37377795
http://dx.doi.org/10.1177/11779322231182050

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