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Impact of renal tubular Cpt1a overexpression on the kidney metabolome in the folic acid-induced fibrosis mouse model

Background: Chronic kidney disease (CKD) is characterized by the progressive and irreversible deterioration of kidney function and structure with the appearance of renal fibrosis. A significant decrease in mitochondrial metabolism, specifically a reduction in fatty acid oxidation (FAO) in tubular ce...

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Detalles Bibliográficos
Autores principales: Cuevas-Delgado, Paula, Miguel, Verónica, Rupérez, Francisco J., Lamas, Santiago, Barbas, Coral
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291237/
https://www.ncbi.nlm.nih.gov/pubmed/37377862
http://dx.doi.org/10.3389/fmolb.2023.1161036