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Delineating effects of angiopoietin-2 inhibition on vascular permeability and inflammation in models of retinal neovascularization and ischemia/reperfusion

INTRODUCTION: Clinical trials demonstrated that co-targeting angiopoietin-2 (Ang-2) and vascular endothelial growth factor (VEGF-A) with faricimab controls anatomic outcomes and maintains vision improvements, with strong durability, through 2 years in patients with neovascular age-related macular de...

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Detalles Bibliográficos
Autores principales: Canonica, Jérémie, Foxton, Richard, Garrido, Marina Garcia, Lin, Cheng-Mao, Uhles, Sabine, Shanmugam, Sumathi, Antonetti, David A., Abcouwer, Steven F., Westenskow, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291265/
https://www.ncbi.nlm.nih.gov/pubmed/37377777
http://dx.doi.org/10.3389/fncel.2023.1192464