Synthesis, ADMT prediction, and in vitro and in silico α-glucosidase inhibition evaluations of new quinoline–quinazolinone–thioacetamides

In this work, a new series of quinoline–quinazolinone–thioacetamide derivatives 9a–p were designed using a combination of effective pharmacophores of the potent α-glucosidase inhibitors. These compounds were synthesized by simple chemical reactions and evaluated for their anti-α-glucosidase activity...

Descripción completa

Detalles Bibliográficos
Autores principales: Safapoor, Sajedeh, Halimi, Mohammad, Ghomi, Minoo Khalili, Noori, Milad, Dastyafteh, Navid, Javanshir, Shahrzad, Hosseini, Samanesadat, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Nasli-Esfahani, Ensieh, Larijani, Bagher, Fakhrioliaei, Azadeh, Dekamin, Mohammad G., Mohammadi-Khanaposhtani, Maryam, Mahdavi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291282/
https://www.ncbi.nlm.nih.gov/pubmed/37377867
http://dx.doi.org/10.1039/d3ra01790g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291282/
https://www.ncbi.nlm.nih.gov/pubmed/37377867
http://dx.doi.org/10.1039/d3ra01790g

Ejemplares similares