How chromosomal translocations arise to cause cancer: Gene proximity, trans-splicing, and DNA end joining

Chromosomal translocations (CTs) are a genetic hallmark of cancer. They could be identified as recurrent genetic aberrations in hemato-malignancies and solid tumors. More than 40% of all “cancer genes” were identified in recurrent CTs. Most of these CTs result in the production of oncofusion protein...

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Detalles Bibliográficos
Autores principales: Streb, Patrick, Kowarz, Eric, Benz, Tamara, Reis, Jennifer, Marschalek, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291325/
https://www.ncbi.nlm.nih.gov/pubmed/37378346
http://dx.doi.org/10.1016/j.isci.2023.106900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291325/
https://www.ncbi.nlm.nih.gov/pubmed/37378346
http://dx.doi.org/10.1016/j.isci.2023.106900

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