A purinergic mechanism underlying metformin regulation of hyperglycemia

Metformin, created in 1922, has been the first-line therapy for treating type 2 diabetes mellitus for almost 70 years; however, its mechanism of action remains controversial, partly because most prior studies used supratherapeutic concentrations exceeding 1 mM despite therapeutical blood concentrati...

Descripción completa

Detalles Bibliográficos
Autores principales: Senfeld, Jared, Peng, Qianman, Shi, Yi, Qian, Shenqi, Shen, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291329/
https://www.ncbi.nlm.nih.gov/pubmed/37378329
http://dx.doi.org/10.1016/j.isci.2023.106898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291329/
https://www.ncbi.nlm.nih.gov/pubmed/37378329
http://dx.doi.org/10.1016/j.isci.2023.106898

Ejemplares similares