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The interaction between kynurenine pathway, suicidal ideation and augmentation therapy with minocycline in patients with treatment-resistant depression

BACKGROUND AND AIMS: We investigated kynurenine pathway (KP) metabolites levels and their association with suicidal ideation in patients with treatment-resistant depression (TRD) and elevated peripheral inflammation. The effect of antidepressant augmentation with minocycline on KP metabolites was te...

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Detalles Bibliográficos
Autores principales: Nettis, Maria Antonietta, Lombardo, Giulia, Hastings, Caitlin, Zajkowska, Zuzanna, Mariani, Nicole, Nikkheslat, Naghmeh, Sforzini, Luca, Worrell, Courtney, Begum, Amina, Brown, Mollie, Cleare, Anthony J, Young, Allan H, Pariante, Carmine M, Mondelli, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291376/
https://www.ncbi.nlm.nih.gov/pubmed/37183855
http://dx.doi.org/10.1177/02698811231173588