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Increased fatty acid metabolism and decreased glycolysis are hallmarks of metabolic reprogramming within microglia in degenerating white matter during recovery from experimental stroke

The goal of this study was to evaluate changes in metabolic homeostasis during the first 12 weeks of recovery in a distal middle cerebral artery occlusion mouse model of stroke. To achieve this goal, we compared the brain metabolomes of ipsilateral and contralateral hemispheres from aged male mice u...

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Detalles Bibliográficos
Autores principales: Loppi, Sanna H, Tavera-Garcia, Marco A, Becktel, Danielle A, Maiyo, Boaz K, Johnson, Kristos E, Nguyen, Thuy-Vi V, Schnellmann, Rick G, Doyle, Kristian P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291449/
https://www.ncbi.nlm.nih.gov/pubmed/36772984
http://dx.doi.org/10.1177/0271678X231157298