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Lens regeneration in situ using hESCs-derived cells —similar to natural lens

Lens itself has limited regeneration functionality, thus we aimed to create regenerated lens with biological function to treat cataracts rather than the intraocular lens used in cataract surgery. We induced exogenous human embryonic stem cells to directionally differentiate into lens fate like cells...

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Detalles Bibliográficos
Autores principales: Chen, Xinyi, Wang, Hanle, Chen, Hui, Ren, Ling, Wang, Wei, Xu, Jingjie, Luo, Chenqi, Hu, Peike, Fu, Qiuli, Yao, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291466/
https://www.ncbi.nlm.nih.gov/pubmed/37378332
http://dx.doi.org/10.1016/j.isci.2023.106921