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Temporary serine protease inhibition and the role of SPINK2 in human bone marrow

Protease temporary inhibitors are true substrates that bind the catalytic site with high affinity but are slowly degraded, thus acting as inhibitor for a defined time window. Serine peptidase inhibitor Kazal type (SPINK) family is endowed with such functional property whose physiological meaning is...

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Detalles Bibliográficos
Autores principales: Barresi, Vincenza, Di Bella, Virginia, Lo Nigro, Luca, Privitera, Anna Provvidenza, Bonaccorso, Paola, Scuderi, Chiara, Condorelli, Daniele Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291479/
https://www.ncbi.nlm.nih.gov/pubmed/37378330
http://dx.doi.org/10.1016/j.isci.2023.106949