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A Drosophila model of diabetic neuropathy reveals a role of proteasome activity in the glia

Diabetic peripheral neuropathy (DPN) is the most common chronic, progressive complication of diabetes mellitus. The main symptom is sensory loss; the molecular mechanisms are not fully understood. We found that Drosophila fed a high-sugar diet, which induces diabetes-like phenotypes, exhibit impairm...

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Detalles Bibliográficos
Autores principales: Suzuki, Mari, Kuromi, Hiroshi, Shindo, Mayumi, Sakata, Nozomi, Niimi, Naoko, Fukui, Koji, Saitoe, Minoru, Sango, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291573/
https://www.ncbi.nlm.nih.gov/pubmed/37378316
http://dx.doi.org/10.1016/j.isci.2023.106997