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AKT2-mediated nuclear deformation leads to genome instability during epithelial-mesenchymal transition
Nuclear deformation has been observed in some cancer cells for decades, but its underlying mechanism and biological significance remain elusive. To address these questions, we employed human lung cancer A549 cell line as a model in context with transforming growth factor β (TGFβ)-induced epithelial-...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291577/ https://www.ncbi.nlm.nih.gov/pubmed/37378334 http://dx.doi.org/10.1016/j.isci.2023.106992 |