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Dysregulation of histone modifications in bone marrow mesenchymal stem cells during skeletal ageing: roles and therapeutic prospects

Age-associated bone diseases such as osteoporosis (OP) are common in the elderly due to skeletal ageing. The process of skeletal ageing can be accelerated by reduced proliferation and osteogenesis of bone marrow mesenchymal stem cells (BM-MSCs). Senescence of BM-MSCs is a main driver of age-associat...

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Detalles Bibliográficos
Autores principales: Li, Yujue, Hu, Mingxing, Xie, Jinwei, Li, Shuangqing, Dai, Lunzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291799/
https://www.ncbi.nlm.nih.gov/pubmed/37357311
http://dx.doi.org/10.1186/s13287-023-03393-6