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Adipose tissue-derived human mesenchymal stromal cells can better suppress complement lysis, engraft and inhibit acute graft-versus-host disease in mice

BACKGROUND: Acute graft-versus-host disease (aGvHD) is a life-threatening complication of allogeneic hematopoietic stem cell transplantation (HSCT). Transplantation of immunosuppressive human mesenchymal stromal cells (hMSCs) can protect against aGvHD post-HSCT; however, their efficacy is limited by...

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Detalles Bibliográficos
Autores principales: Wu, Stanley Chun Ming, Zhu, Manyu, Chik, Stanley C. C., Kwok, Maxwell, Javed, Asif, Law, Laalaa, Chan, Shing, Boheler, Kenneth R., Liu, Yin Ping, Chan, Godfrey Chi Fung, Poon, Ellen Ngar-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291819/
https://www.ncbi.nlm.nih.gov/pubmed/37357314
http://dx.doi.org/10.1186/s13287-023-03380-x