Increased intestinal permeability and downregulation of absorptive ion transporters Nhe3, Dra, and Sglt1 contribute to diarrhea during Clostridioides difficile infection

BACKGROUND & AIM: Clostridioides difficile infection (CDI) is the leading cause of hospital-acquired diarrhea and pseudomembranous colitis. Two protein toxins, TcdA and TcdB, produced by C. difficile are the major determinants of disease. However, the pathophysiological causes of diarrhea during...

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Detalles Bibliográficos
Autores principales: Peritore-Galve, F. Christopher, Kaji, Izumi, Smith, Anna, Walker, Lauren M., Shupe, John A., Washington, M. Kay, Algood, Holly M. Scott, Dudeja, Pradeep K., Goldenring, James R., Lacy, D. Borden
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291935/
https://www.ncbi.nlm.nih.gov/pubmed/37350393
http://dx.doi.org/10.1080/19490976.2023.2225841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291935/
https://www.ncbi.nlm.nih.gov/pubmed/37350393
http://dx.doi.org/10.1080/19490976.2023.2225841

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