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Evaluation of phase I clinical trial designs for combinational agents along with guidance based on simulation studies
Combinational therapy that combines two or more therapeutic agents is very common in cancer treatment. Currently, many clinical trials aim to assess feasibility, safety and activity of combinational therapeutics to achieve synergistic response. Dose-finding for combinational agents is considerably m...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10291942/ https://www.ncbi.nlm.nih.gov/pubmed/37378271 http://dx.doi.org/10.1080/02664763.2022.2105827 |