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The ETS transcription factor ERF controls the exit from the naïve pluripotent state in a MAPK-dependent manner

The naïve epiblast transitions to a pluripotent primed state during embryo implantation. Despite the relevance of the FGF pathway during this period, little is known about the downstream effectors regulating this signaling. Here, we examined the molecular mechanisms coordinating the naïve to primed...

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Detalles Bibliográficos
Autores principales: Vega-Sendino, Maria, Olbrich, Teresa, Tillo, Desiree, Tran, Andy D., Domingo, Catherine N., Franco, Mariajose, FitzGerald, Peter C., Kruhlak, Michael J., Ruiz, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292047/
https://www.ncbi.nlm.nih.gov/pubmed/34597136
http://dx.doi.org/10.1126/sciadv.abg8306