Counterfactual estimation of efficacy against placebo for novel PrEP agents using external trial data: example of injectable cabotegravir and oral PrEP in women

INTRODUCTION: Multiple antiretroviral agents have demonstrated efficacy for human immunodeficiency virus (HIV) pre‐exposure prophylaxis (PrEP). As a result, clinical trials of novel agents have transitioned from placebo‐ to active‐controlled designs; however, active‐controlled trials do not provide...

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Detalles Bibliográficos
Autores principales: Donnell, Deborah, Gao, Fei, Hughes, James P., Hanscom, Brett, Corey, Lawrence, Cohen, Myron S., Edupuganti, Srilatha, Mgodi, Nyaradzo, Rees, Helen, Baeten, Jared M., Gray, Glenda, Bekker, Linda‐Gail, Hosseinipour, Mina, Delany‐Moretlwe, Sinead
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292682/
https://www.ncbi.nlm.nih.gov/pubmed/37363917
http://dx.doi.org/10.1002/jia2.26118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292682/
https://www.ncbi.nlm.nih.gov/pubmed/37363917
http://dx.doi.org/10.1002/jia2.26118

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