Mutators can drive the evolution of multi-resistance to antibiotics

Antibiotic combination therapies are an approach used to counter the evolution of resistance; their purported benefit is they can stop the successive emergence of independent resistance mutations in the same genome. Here, we show that bacterial populations with ‘mutators’, organisms with defects in...

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Detalles Bibliográficos
Autores principales: Gifford, Danna R., Berríos-Caro, Ernesto, Joerres, Christine, Suñé, Marc, Forsyth, Jessica H., Bhattacharyya, Anish, Galla, Tobias, Knight, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292718/
https://www.ncbi.nlm.nih.gov/pubmed/37311005
http://dx.doi.org/10.1371/journal.pgen.1010791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292718/
https://www.ncbi.nlm.nih.gov/pubmed/37311005
http://dx.doi.org/10.1371/journal.pgen.1010791

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