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A new gene-scoring method for uncovering novel glaucoma-related genes using non-negative matrix factorization based on RNA-seq data

Early diagnosis and treatment of glaucoma are challenging. The discovery of glaucoma biomarkers based on gene expression data could potentially provide new insights for early diagnosis, monitoring, and treatment options of glaucoma. Non-negative Matrix Factorization (NMF) has been widely used in num...

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Detalles Bibliográficos
Autores principales: Huang, Xiaoqin, Bajpai, Akhilesh K., Sun, Jian, Xu, Fuyi, Lu, Lu, Yousefi, Siamak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292752/
https://www.ncbi.nlm.nih.gov/pubmed/37377596
http://dx.doi.org/10.3389/fgene.2023.1204909