Inhibition of γ-glutamyl transferase suppresses airway hyperresponsiveness and airway inflammation in a mouse model of steroid resistant asthma exacerbation

INTRODUCTION: Despite recent advances, there are limited treatments available for acute asthma exacerbations. Here, we investigated the therapeutic potential of GGsTop, a γ-glutamyl transferase inhibitor, on the disease with a murine model of asthma exacerbation. METHODS: GGsTop was administered to...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Cancan, Xu, Huisha, Netto, Keilah G., Sokulsky, Leon A., Miao, Yiyan, Mo, Zhongyuan, Meng, Yan, Du, Yingying, Wu, Chengyong, Han, Liyou, Zhang, Lirong, Liu, Chi, Zhang, Guojun, Li, Fuguang, Yang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292800/
https://www.ncbi.nlm.nih.gov/pubmed/37377967
http://dx.doi.org/10.3389/fimmu.2023.1132939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292800/
https://www.ncbi.nlm.nih.gov/pubmed/37377967
http://dx.doi.org/10.3389/fimmu.2023.1132939

Ejemplares similares