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Inhibition of γ-glutamyl transferase suppresses airway hyperresponsiveness and airway inflammation in a mouse model of steroid resistant asthma exacerbation

INTRODUCTION: Despite recent advances, there are limited treatments available for acute asthma exacerbations. Here, we investigated the therapeutic potential of GGsTop, a γ-glutamyl transferase inhibitor, on the disease with a murine model of asthma exacerbation. METHODS: GGsTop was administered to...

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Detalles Bibliográficos
Autores principales:	Zhang, Cancan, Xu, Huisha, Netto, Keilah G., Sokulsky, Leon A., Miao, Yiyan, Mo, Zhongyuan, Meng, Yan, Du, Yingying, Wu, Chengyong, Han, Liyou, Zhang, Lirong, Liu, Chi, Zhang, Guojun, Li, Fuguang, Yang, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292800/ https://www.ncbi.nlm.nih.gov/pubmed/37377967 http://dx.doi.org/10.3389/fimmu.2023.1132939

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