Columbianadin attenuates doxorubicin-induced cardiac injury, oxidative stress, and apoptosis via Sirt1/FOXO1 signaling pathway

PURPOSE: Oxidative stress and apoptosis contribute to the pathological basis of doxorubicin (DOX)-induced cardiotoxicity. Columbianadin (CBN) is one of the main bioactive constituents isolated from the root of Angelica pubescens. Herein, we intended to explore the potential role and molecular basis...

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Detalles Bibliográficos
Autores principales: Peng, Bo, Rao, Li, Yang, Jiaolong, Ku, Xiaowei, Kong, Bin, Shuai, Wei, Huang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292807/
https://www.ncbi.nlm.nih.gov/pubmed/37377248
http://dx.doi.org/10.1590/acb382223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292807/
https://www.ncbi.nlm.nih.gov/pubmed/37377248
http://dx.doi.org/10.1590/acb382223

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