Old-age-induced obesity reversed by a methionine-deficient diet or oral administration of recombinant methioninase-producing Escherichia coli in C57BL/6 mice

Obesity increases with aging. Methionine restriction affects lipid metabolism and can prevent obesity in mice. In the present study we observed C57BL/6 mice to double their body weight from 4 to 48 weeks of age and become obese. We evaluated the efficacy of oral administration of recombinant-methion...

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Detalles Bibliográficos
Autores principales: Kubota, Yutaro, Han, Qinghong, Reynoso, Jose, Aoki, Yusuke, Masaki, Noriyuki, Obara, Koya, Hamada, Kazuyuki, Bouvet, Michael, Tsunoda, Takuya, Hoffman, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292902/
https://www.ncbi.nlm.nih.gov/pubmed/37301544
http://dx.doi.org/10.18632/aging.204783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292902/
https://www.ncbi.nlm.nih.gov/pubmed/37301544
http://dx.doi.org/10.18632/aging.204783

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