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PZR promotes tumorigenicity of lung cancer cells by regulating cell migration and invasion via modulating oxidative stress and cell adhesion

PZR is a transmembrane glycoprotein encoded by the MPZL1 gene. It serves as a specific binding protein and substrate of tyrosine phosphatase SHP-2 whose mutations cause developmental diseases and cancers. Bioinformatic analyses of cancer gene databases revealed that PZR is overexpressed in lung canc...

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Detalles Bibliográficos
Autores principales: Fu, Ying, Sui, Yuan, Zhao, Yuming, Jiang, Jianzhuo, Wang, Xueyuan, Cui, Jiarui, Fu, Xueqi, Xing, Shu, Zhao, Zhizhuang Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292906/
https://www.ncbi.nlm.nih.gov/pubmed/37279992
http://dx.doi.org/10.18632/aging.204771