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PZR promotes tumorigenicity of lung cancer cells by regulating cell migration and invasion via modulating oxidative stress and cell adhesion
PZR is a transmembrane glycoprotein encoded by the MPZL1 gene. It serves as a specific binding protein and substrate of tyrosine phosphatase SHP-2 whose mutations cause developmental diseases and cancers. Bioinformatic analyses of cancer gene databases revealed that PZR is overexpressed in lung canc...
Autores principales: | Fu, Ying, Sui, Yuan, Zhao, Yuming, Jiang, Jianzhuo, Wang, Xueyuan, Cui, Jiarui, Fu, Xueqi, Xing, Shu, Zhao, Zhizhuang Joe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10292906/ https://www.ncbi.nlm.nih.gov/pubmed/37279992 http://dx.doi.org/10.18632/aging.204771 |
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