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Phenotypic diversity of T cells in human primary and metastatic brain tumors revealed by multiomic interrogation

The immune-specialized environment of the healthy brain is tightly regulated to prevent excessive neuroinflammation. However, after cancer development, a tissue-specific conflict between brain-preserving immune suppression and tumor-directed immune activation may ensue. To interrogate potential role...

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Detalles Bibliográficos
Autores principales: Wischnewski, Vladimir, Maas, Roeltje R., Aruffo, Paola Guerrero, Soukup, Klara, Galletti, Giovanni, Kornete, Mara, Galland, Sabine, Fournier, Nadine, Lilja, Johanna, Wirapati, Pratyaksha, Lourenco, Joao, Scarpa, Alice, Daniel, Roy T., Hottinger, Andreas F., Brouland, Jean-Philippe, Losurdo, Agnese, Voulaz, Emanuele, Alloisio, Marco, Hegi, Monika E., Lugli, Enrico, Joyce, Johanna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293012/
https://www.ncbi.nlm.nih.gov/pubmed/37217652
http://dx.doi.org/10.1038/s43018-023-00566-3