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Phenotypic diversity of T cells in human primary and metastatic brain tumors revealed by multiomic interrogation
The immune-specialized environment of the healthy brain is tightly regulated to prevent excessive neuroinflammation. However, after cancer development, a tissue-specific conflict between brain-preserving immune suppression and tumor-directed immune activation may ensue. To interrogate potential role...
Autores principales: | Wischnewski, Vladimir, Maas, Roeltje R., Aruffo, Paola Guerrero, Soukup, Klara, Galletti, Giovanni, Kornete, Mara, Galland, Sabine, Fournier, Nadine, Lilja, Johanna, Wirapati, Pratyaksha, Lourenco, Joao, Scarpa, Alice, Daniel, Roy T., Hottinger, Andreas F., Brouland, Jean-Philippe, Losurdo, Agnese, Voulaz, Emanuele, Alloisio, Marco, Hegi, Monika E., Lugli, Enrico, Joyce, Johanna A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293012/ https://www.ncbi.nlm.nih.gov/pubmed/37217652 http://dx.doi.org/10.1038/s43018-023-00566-3 |
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