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The copper chelator ammonium tetrathiomolybdate inhibits the progression of experimental endometriosis in TNFR1-deficient mice

The TNF-α/TNFR system is involved in endometriosis (EDT), a gynecologic estrogen-dependent disease. Elevated copper concentrations have also been associated with EDT, even in TNFR1-deficient mice where disease worsening occurs. We aimed to evaluate whether treatment with ammonium tetrathiomolybdate...

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Detalles Bibliográficos
Autores principales: Conforti, Rocío Ayelem, Delsouc, María Belén, Zabala, Ana Sofia, Vallcaneras, Sandra Silvina, Casais, Marilina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293193/
https://www.ncbi.nlm.nih.gov/pubmed/37365216
http://dx.doi.org/10.1038/s41598-023-37031-1