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Myeloid-derived growth factor alleviates non-alcoholic fatty liver disease alleviates in a manner involving IKKβ/NF-κB signaling

Whether bone marrow modulates systemic metabolism remains unknown. Our recent study suggested that myeloid-derived growth factor (MYDGF) improves insulin resistance. Here, we found that myeloid cell-specific MYDGF deficiency aggravated hepatic inflammation, lipogenesis, and steatosis, and show that...

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Detalles Bibliográficos
Autores principales: Ding, Yan, Xu, Xiaoli, Meng, Biying, Wang, Li, Zhu, Biao, Guo, Bei, Zhang, Jiajia, Xiang, Lin, Dong, Jing, Liu, Min, Xiang, Guangda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293205/
https://www.ncbi.nlm.nih.gov/pubmed/37365185
http://dx.doi.org/10.1038/s41419-023-05904-y