Cargando…

Myeloid-derived growth factor alleviates non-alcoholic fatty liver disease alleviates in a manner involving IKKβ/NF-κB signaling

Whether bone marrow modulates systemic metabolism remains unknown. Our recent study suggested that myeloid-derived growth factor (MYDGF) improves insulin resistance. Here, we found that myeloid cell-specific MYDGF deficiency aggravated hepatic inflammation, lipogenesis, and steatosis, and show that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ding, Yan, Xu, Xiaoli, Meng, Biying, Wang, Li, Zhu, Biao, Guo, Bei, Zhang, Jiajia, Xiang, Lin, Dong, Jing, Liu, Min, Xiang, Guangda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293205/ https://www.ncbi.nlm.nih.gov/pubmed/37365185 http://dx.doi.org/10.1038/s41419-023-05904-y

Ejemplares similares

Myeloid-derived growth factor inhibits inflammation and alleviates endothelial injury and atherosclerosis in mice
por: Meng, Biying, et al.
Publicado: (2021)

Brown adipose tissue-derived Nrg4 alleviates endothelial inflammation and atherosclerosis in male mice
por: Shi, Lingfeng, et al.
Publicado: (2022)

Author Correction: Brown adipose tissue-derived Nrg4 alleviates endothelial inflammation and atherosclerosis in male mice
por: Shi, Lingfeng, et al.
Publicado: (2022)

TfR1 interacts with the IKK complex and is involved in IKK–NF-κB signalling
por: Kenneth, Niall S., et al.
Publicado: (2012)

Attribution of NF-κB Activity to CHUK/IKKα-Involved Carcinogenesis
por: Li, Xin, et al.
Publicado: (2021)

IKKβ/NF-κB and the miscreant macrophage
por: Timmer, Anjuli M., et al.
Publicado: (2008)

Hypothalamic Programming of Systemic Aging Involving IKKβ/NF-κB and GnRH
por: Zhang, Guo, et al.
Publicado: (2013)

Inhibition of Osteoblast Functions by IKK/NF-κB in Osteoporosis
por: Chang, Jia, et al.
Publicado: (2009)

Local and Systemic IKKε and NF-κB Signaling Associated with Sjögren's Syndrome Immunopathogenesis
por: Chen, Weiqian, et al.
Publicado: (2015)

Rapamycin Pretreatment Alleviates Cerebral Ischemia/Reperfusion Injury in Dose-Response Manner Through Inhibition of the Autophagy and NFκB Pathways in Rats
por: Li, Liru, et al.
Publicado: (2020)

Role of IKK/NF-κB Signaling in Extinction of Conditioned Place Aversion Memory in Rats
por: Yang, Cheng-Hao, et al.
Publicado: (2012)

IKKα and IKKβ Each Function to Regulate NF-κB Activation in the TNF-Induced/Canonical Pathway
por: Adli, Mazhar, et al.
Publicado: (2010)

Her2 Activates NF-κB and Induces Invasion Through the Canonical Pathway Involving IKKα
por: Merkhofer, Evan C, et al.
Publicado: (2009)

Cytosolic Hsp60 Is Involved in the NF-κB-Dependent Survival of Cancer Cells via IKK Regulation
por: Chun, Jung Nyeo, et al.
Publicado: (2010)

Rosiglitazone alleviates lipopolysaccharide-induced inflammation in RAW264.7 cells via inhibition of NF-κB and in a PPARγ-dependent manner
por: Zhou, Jing-Ping, et al.
Publicado: (2021)

Benefits of Combining Sonchus brachyotus DC. Extracts and Synbiotics in Alleviating Non-Alcoholic Fatty Liver Disease
por: Huang, Wenwu, et al.
Publicado: (2023)

Crosstalk between the NF-κB activating IKK-complex and the CSN signalosome
por: Orel, Lukas, et al.
Publicado: (2010)

Hypoxia activates IKK–NF-κB and the immune response in Drosophila melanogaster
por: Bandarra, Daniel, et al.
Publicado: (2014)

IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance
por: Rinkenbaugh, Amanda L., et al.
Publicado: (2016)

NF‐κB/IKK activation by small extracellular vesicles within the SASP
por: Fafián‐Labora, Juan Antonio, et al.
Publicado: (2021)

Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
por: Zhang, Kun, et al.
Publicado: (2023)

Overexpression of IκBα in cardiomyocytes alleviates hydrogen peroxide-induced apoptosis and autophagy by inhibiting NF-κB activation
por: Han, Min, et al.
Publicado: (2020)

Blocking Notch signal in myeloid cells alleviates hepatic ischemia reperfusion injury by repressing the activation of NF-κB through CYLD
por: Yu, Heng-Chao, et al.
Publicado: (2016)

Rhoifolin Alleviates Alcoholic Liver Disease In Vivo and In Vitro via Inhibition of the TLR4/NF-κB Signaling Pathway
por: Mai, Baoyu, et al.
Publicado: (2022)

Nuclear Receptor-Mediated Alleviation of Alcoholic Fatty Liver by Polyphenols Contained in Alcoholic Beverages
por: Yao, Ruiqing, et al.
Publicado: (2014)

Wogonin alleviates liver injury in sepsis through Nrf2‐mediated NF‐κB signalling suppression
por: Dai, Ji‐Min, et al.
Publicado: (2021)

Tubular IKKβ Deletion Alleviates Acute Ischemic Kidney Injury and Facilitates Tissue Regeneration
por: Dahlke, Eileen, et al.
Publicado: (2022)

Captopril alleviates hypertension-induced renal damage, inflammation, and NF-κB activation
por: Gan, Zhongyuan, et al.
Publicado: (2018)

Salidroside Alleviates Cartilage Degeneration Through NF-κB Pathway in Osteoarthritis Rats
por: Gao, Hui, et al.
Publicado: (2020)

Oxycodone Alleviates Endometrial Injury via the TLR4/NF-κB Pathway
por: Zhu, Aibing, et al.
Publicado: (2022)

Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF-κB Pathway
por: Li, Sunlong, et al.
Publicado: (2022)

Dendrobine Alleviates Cellular Senescence and Osteoarthritis via the ROS/NF-κB Axis
por: Chen, Haitao, et al.
Publicado: (2023)

New Mechanisms of Bromelain in Alleviating Non-Alcoholic Fatty Liver Disease-Induced Deregulation of Blood Coagulation
por: Hu, Po-An, et al.
Publicado: (2022)

Uncoupling Obesity-related Hypertension by Targeting Hypothalamic IKKβ/NF-κB
por: Purkayastha, Sudarshana, et al.
Publicado: (2011)

Constitutive Activation of IKK2/NF-κB Impairs Osteogenesis and Skeletal Development
por: Swarnkar, Gaurav, et al.
Publicado: (2014)

PHLPP2 suppresses the NF-κB pathway by inactivating IKKβ kinase
por: Agarwal, Nitin Kumar, et al.
Publicado: (2014)

Trichosanthes kirilowii lectin alleviates diabetic nephropathy by inhibiting the LOX1/NF-κB/caspase-9 signaling pathway
por: Lu, Jiandong, et al.
Publicado: (2018)

The BH3-only protein BAD mediates TNFα cytotoxicity despite concurrent activation of IKK and NF-κB in septic shock
por: Yan, Jie, et al.
Publicado: (2018)

Daucosterol Alleviates Alcohol−Induced Hepatic Injury and Inflammation through P38/NF−κB/NLRP3 Inflammasome Pathway
por: Zhang, Feng, et al.
Publicado: (2023)

Pathophysiology of osteoarthritis: canonical NF-κB/IKKβ-dependent and kinase-independent effects of IKKα in cartilage degradation and chondrocyte differentiation
por: Olivotto, Eleonora, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_jn1alna084oj0fa6v1nkj00euk