Understanding the mechanism of action and clinical effects of neuroactive steroids and GABAergic compounds in major depressive disorder

The pathophysiology of major depressive disorder (MDD) is thought to result from impaired connectivity between key brain networks. Gamma-aminobutyric acid (GABA) is the key inhibitory neurotransmitter in the brain, working primarily via GABA(A) receptors, with an important role in virtually all phys...

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Detalles Bibliográficos
Autores principales: Cutler, Andrew J., Mattingly, Gregory W., Maletic, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293235/
https://www.ncbi.nlm.nih.gov/pubmed/37365161
http://dx.doi.org/10.1038/s41398-023-02514-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293235/
https://www.ncbi.nlm.nih.gov/pubmed/37365161
http://dx.doi.org/10.1038/s41398-023-02514-2

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