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Understanding the mechanism of action and clinical effects of neuroactive steroids and GABAergic compounds in major depressive disorder
The pathophysiology of major depressive disorder (MDD) is thought to result from impaired connectivity between key brain networks. Gamma-aminobutyric acid (GABA) is the key inhibitory neurotransmitter in the brain, working primarily via GABA(A) receptors, with an important role in virtually all phys...
Autores principales: | Cutler, Andrew J., Mattingly, Gregory W., Maletic, Vladimir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293235/ https://www.ncbi.nlm.nih.gov/pubmed/37365161 http://dx.doi.org/10.1038/s41398-023-02514-2 |
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