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Enriched environmental exposure reduces the onset of action of the serotonin norepinephrin reuptake inhibitor venlafaxine through its effect on parvalbumin interneurons plasticity in mice

Mood disorders are associated with hypothalamic-pituitary-adrenal axis overactivity resulting from a decreased inhibitory feedback exerted by the hippocampus on this brain structure. Growing evidence suggests that antidepressants would regulate hippocampal excitatory/inhibitory balance to restore an...

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Detalles Bibliográficos
Autores principales: Coutens, Basile, Lejards, Camille, Bouisset, Guillaume, Verret, Laure, Rampon, Claire, Guiard, Bruno P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293286/
https://www.ncbi.nlm.nih.gov/pubmed/37365183
http://dx.doi.org/10.1038/s41398-023-02519-x